cpa.ComPertAPI.get_response2D

ComPertAPI.get_response2D(perturbations, covar, doses=None, contvar_min=None, contvar_max=None, n_points=10, ncells_max=100, fixed_drugs='', fixed_doses='')

Decoded dose response data frame.

Parameters:

perturbations list

List of length 2 of perturbations for dose response.

covar str

Name of a covariate for which to compute dose-response.

doses np.array (default: None)

Doses values. If None, default values will be generated on a grid: n_points in range [contvar_min, contvar_max].

contvar_min float (default: 0)

Minimum dose value to generate for default option.

contvar_max float (default: 0)

Maximum dose value to generate for default option.

n_points int (default: 100)

Number of dose points to generate for default option.

Returns:

pd.DataFrame of decoded response values of genes and average response.